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Wound Healing PowerPoint Presentation

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Description : Check out this medical PowerPoint presentation titled "WOUND HEALING" Dr. Sanjeev Kumar.

This medical PowerPoint presentation is about wound healing, the natural biological process by which the body repairs damaged tissue. It is a complex process involving multiple stages and various types of cells and molecules. The goal of wound healing is to restore the integrity and function of damaged tissue, prevent infection, and minimize scarring.

There are three main stages of wound healing: inflammation, proliferation, and remodeling. In the inflammation stage, damaged tissue is cleared away by the immune system, and the wound becomes inflamed. This stage typically lasts for a few days. In the proliferation stage, new tissue is generated to fill the wound, and blood vessels begin to grow into the wound. This stage can last several weeks. In the remodeling stage, the newly generated tissue is remodeled and strengthened, and the wound gradually closes. This stage can last for several months.

There are many factors that can affect wound healing, including the type and size of the wound, the age and health of the individual, and the presence of underlying medical conditions such as diabetes or cardiovascular disease. Factors such as poor nutrition, smoking, and stress can also slow down the wound healing process.

Treatment for wound healing may include keeping the wound clean and protected, applying topical medications or dressings, taking oral medications, and in some cases, undergoing surgical procedures. Proper wound care is essential to prevent infection and promote healing.

Tags : wound healing, Orthopaedic Surgery, Orthopaedic Surgery PowerPoint presentation

Published on : Jun 23, 2023 | Views : 737 | Downloads : 5

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Slide 1-

WOUND HEALING DR SANJIV KUMAR
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Introduction DR SANJIV KUMAR
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HEALING OCCURS BY 1. HEALING BY REGENERATION 2. HEALING BY REPAIR/SUBSTITUTION DR SANJIV KUMAR
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Labile cells - Continuously dividing cells. e.g. epidermis, epithelial cells, bone marrow cells Stable cells/Quiescent cells • Undergoes division occasionally • Liver, kidney pancreas, fibroblasts, endothelial cells Permanent cells • Non–dividing cells • Neurons, muscle cells (cardiac, skeletal) DR SANJIV KUMAR
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Types of Wound Healing DR SANJIV KUMAR
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Healing by first Intention DR SANJIV KUMAR
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Stages of Wound Healing INFLAMMATORY PHASE PROLIFERATIVE PHASE MATURATION AND REMODELING PHASE DR SANJIV KUMAR
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Angiogenesis DR SANJIV KUMAR
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Maturation Phase DR SANJIV KUMAR
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Inflammation subsides Decreased fibroblasts & EC Myoid differentiation of fibroblasts leading to wound contraction Crosslinking of collagen into thicker bundles Proteolysis Further contraction Further crosslinking… Remodeling & Scaring DR SANJIV KUMAR
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The wound involved shows extensive loss of cells and tissue. e.g. infarction, ulceration, abscesses, surface wound with large defects. The wound is filled with tissue debris, a few erythrocytes and bacteria. Abundant granulation tissue (soft, pink, granular appearance of wound surfaces) grows in from the margin to fill the defect but at the same time the wound contracts i.e., the defect is marked by depression and decrease from its original size. Microscopically granulation tissue consists of new capillaries, fibroblasts, collagen and proteoglycan rich ground substance. Initially granulation tissue is soft and spongy due to leaky blood vessels. Healing by Second Intention DR SANJIV KUMAR
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Difference b/w Primary and Secondary intention DR SANJIV KUMAR
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Exuberant granulation or proud flesh Sometimes the granulation continues to grow in abnormally large amount due to irritant, movement or trauma which prevents healing. This condition is called proud flesh or excess granulation tissue. Keloid Keloid is another condition. The connective tissue below the epithelial covering continues to proliferate. This is found in horses and black people having some genetic or familial predisposition. Complication DR SANJIV KUMAR
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Systemic factors Nutritional Vitamins – vitamin C is required for collagen synthesis Proteins deficiency – starvation Sulphur containing amino acids (methionine and cystine) are important and required for intermediate forms of collagen Zinc – as metalloenzyme, it is essential for remodelling of extracellular matrix Metabolic factors Diabetes mellitus – delays healing Hyperadrenocortism Circulatory stasis or adequacy of blood supply Inadequate blood supply – delays healing Hormones – concurrent glucocorticoid therapy hinders inflammatory and reparatory process Systemic and local factors influencing wound healing DR SANJIV KUMAR
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Local factors Infection can delay healing Mechanical – movements directly affect wound healing Foreign bodies impede healing Size, location and type of wound Cold inhibits wound healing Others Old age-Healing is slower than young ones. Chemotherapeutic agents Radiation Immunodeficiency DR SANJIV KUMAR