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Treatment Options for Infertility PowerPoint Presentation

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Description : Check out this medical presentation on Obstetrics & Gynecology, which is titled "Treatment Options for Infertility", to know about infertility treatment options available for females and males, and available ovulation-inducing drugs.

Tags : Obstetrics, Gynecology, Treatment Options, Infertility, females, males, ovulation-inducing drugs

Published on : Jul 18, 2021 | Views : 1451 | Downloads : 4

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Slide 1-

Treatment Options for Infertility Association of Reproductive Health Professionals www.arhp.org
Slide 2-

Learning Objectives State at least three infertility treatment options available for females. State at least three infertility treatment options available for males. List two available ovulation-inducing drugs.
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Basic Services for Infertile Couples Stewart GK. 1998 2. Conduct appropriate diagnostic workup
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Fertility Treatments Can Work ‘ ‘ “…With thorough evaluation and application of current treatments short of IVF, embryo transfer, or GIFT, 50–60% of infertility couples will conceive.” Meldrum DR. 1998. Meldrum DR 1998
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Causes & Treatments for Male Infertility Azospermia Surgical sterilization Inject FSH and LH Impaired sperm motility Reverse vasectomy Repair varicocele Nelson AL, Marshall JR. 2004.
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Main Causes of Female Infertility Ovulation disorders Endometriosis Tubal abnormalities Nelson AL, Marshall JR. 2004.
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Treatments for Female Infertility Ovulation disorders Endometriosis Tubal abnormalities Maintain normal body weight Clomiphene Metformin Gonadotropin therapies Laparoscopic ovarian drilling Nelson AL, Marshall JR. 2004. more…
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Treatments for Female Infertility (continued) Endometriosis Tubal abnormalities Tubal abnormalities In vitro fertilization With or without salpingectomy Tuboplasty (tubal ligation reversal) Nelson AL, Marshall JR. 2004. more…
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Treatments for Female Infertility (continued) Endometriosis Tubal abnormalities Endometriosis Laparoscopic ablation Intrauterine insemination with controlled hyperstimulation In vitro fertilization Nelson AL, Marshall JR. 2004.
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Ovulation-Inducing Drugs: Clomiphene Chemically stimulates pituitary gland to produce hormones that trigger ovulation process Usual dosage: 50 mg/day for 5 days Numerous side effects May not be appropriate for patients with: Large fibroid tumors Ovarian cysts Liver problems Harkness C. The Infertility Book. 1992. more…
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Ovulation-Inducing Drugs: Bromocriptine Reduces production of prolactin hormone Dosage: 2.5 mg 1–3 times/day Some side effects May not be appropriate for patients with pituitary tumors >1 cm Harkness C. The Infertility Book. 1992.
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Ovulation-Inducing Drugs Human Menopausal Gonadotropins (hMG) Follicle-Stimulating Hormone (FSH) Stimulate ovary to develop follicles 75–150 IU/day (with hCG) 20–40% possibility of multiple births May not be appropriate in cases of pituitary tumor, ovarian cysts Harkness C. The Infertility Book. 1992. more…
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Ovulation-Inducing Drugs (continued) Gonadotropin-Releasing Hormone (GnRH) Triggers normal pituitary hormonal activity so ovulation can occur Effective in women with hypothalamic amenorrhea No known physical side effects Ovulation pump administers injections every 90 minutes User must carry pump with attached IV tubing for 1–2 weeks or until ovulation occurs Harkness C. The Infertility Book. 1992.
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Endometriosis: Treatment with Surgery Pregnancy rates after surgery ≤60% 45–75% 35–48% After Stage 1 or 2 Stage 3 Stage 4 Jennings VH, et al. 1998.
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Endometriosis: Drug Therapies GnRH agonists Birth control pills Jennings VH, et al. 1998.
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Polycystic Ovarian Disease: Treatment Ovulation induction Clomiphene HMG, FSH, GnRH Insulin sensitizers (e.g. metformin, rosiglitazone) Jennings VH, et al. 1998.
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ART Treatments for Infertility American Society for Reproductive Medicine. 2003. American Society for Reproductive Medicine. 2001. A IVF with embryo transfer Gamete intrafallopian transfer (GIFT) Zygote intrafallopian transfer (ZIFT) Cryopreservation Intracytoplasmic sperm injection (ICSI) T R
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IVF with Embryo Transfer Clapp DN. 2002. Egg and sperm are retrieved from couple, donor(s), or both Combined in a petri dish, incubated for 2–5 days If fertilization and cleavage occurs, embryo is transferred through a catheter to uterus
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Gamete Intrafallopian Transfer (GIFT) Clapp DN. 2002. Oocytes retrieved via laparoscopy Oocytes and sperm placed in same catheter Injected directly into the fallopian tube via laparoscopy Embryo travels through the fallopian tube to the uterus for implantation
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Zygote Intrafallopian Transfer (ZIFT) Combines techniques used in IVF and GIFT Clapp DN. 2002. Ova are placed in a petri dish with sperm If fertilization occurs, the zygote: Is injected into fallopian tube Travels through tube to uterus Implants in uterus
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Cryopreservation Sperm or embryos are preserved by freezing for replacement in subsequent cycles Clapp DN. 2002. Photo source: http://www.dcmsonline.org
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Intracytoplasmic Sperm Injection (ICSI) A single sperm is injected directly into the cytoplasm of the oocyte Increases probability of fertilization American Society for Reproductive Medicine. 2004. Photo source: www.fertilitycentre.ca
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ART Options for Same-Sex Couples Combination of their own and donor sperm and eggs through IVF Surrogacy Can parent biological children Bateman S. 2004.