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Integration of Metabolism PowerPoint Presentation

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Description : Check out this medical PowerPoint presentation titled "Integration of Metabolism"by Penne Mott.

This medical PowerPoint presentation talks about integration of metabolism, the coordination and regulation of the various biochemical pathways that occur within an organism to maintain energy balance and meet the physiological needs of the body. This involves the integration of pathways that generate and consume energy, such as glucose metabolism, lipid metabolism, and amino acid metabolism.

One of the primary regulators of metabolism is the hormone insulin, which is secreted by the pancreas in response to high blood glucose levels. Insulin promotes the uptake and utilization of glucose by cells throughout the body, including muscle and adipose tissue, and also promotes the storage of excess glucose as glycogen in the liver and muscle.

In addition to insulin, other hormones and signaling molecules also play important roles in regulating metabolism. For example, glucagon is secreted by the pancreas in response to low blood glucose levels and stimulates the breakdown of glycogen in the liver to release glucose into the bloodstream. The hormone leptin, which is produced by adipose tissue, signals to the brain to regulate appetite and energy expenditure.

The integration of metabolism also involves the coordination of various metabolic pathways in different tissues and organs. For example, the liver plays a key role in regulating glucose and lipid metabolism, while muscle tissue is responsible for the majority of glucose uptake and utilization during exercise. Adipose tissue stores and releases energy in the form of triglycerides, and also produces a variety of signaling molecules that influence metabolism.

Overall, the integration of metabolism is essential for maintaining energy homeostasis and ensuring that the body has a constant supply of energy to meet its physiological needs. Disruptions in this process can lead to metabolic disorders such as diabetes, obesity, and metabolic syndrome.

Tags : integration of metabolism, biochemical pathways, glucose metabolism, lipid metabolism, amino acid metabolism, endocrinology, endocrinology PowerPoint presentation

Published on : Apr 18, 2023 | Views : 1044 | Downloads : 5

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Slide 1-

Integration of Metabolism
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Insulin regulation Glucagon regulation Metabolic Regulation in the Fed State Insulin stimulation: Glucose, amino acids (arg), and GI hormones (secretin) Insulin repression: Epinephrine (stress, i.e., fever or infection)
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Biological Effects of Insulin and Glucagon Glucose uptake Glycogen synthesis Protein synthesis Fat synthesis Gluconeogenesis Glycogen mobilization Lipid mobilization Protein degradation Altered gene expression Glucose uptake Glycogen synthesis Protein synthesis Fat synthesis Gluconeogenesis Glycogen mobilization Ketogenesis Protein degradation Uptake of amino acids INSULIN GLUCAGON
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GLUT4 (insulin-responsive glucose transporter) upregulation at the plasma membrane Effect of Insulin on Glucose Transport
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Only ca. 30% of body protein is available for energy production Energy Reserves During Fasting
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Ketone Bodies are an Alternate Energy Source During Fasting Short-term fast: Fatty acids are source of ketone bodies Long-term fast: Amino acids are source of ketone bodies Favored during fatty acid catabolism due to high NADH/NAD+ ratio slow
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