Giardiasis Medical Presentation

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Giardiasis Kevin Thurman and Grace Niccum
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Disease Most common intestinal disease in the United States Popularly known as Beaver Fever Major worldwide cause of diarrheal illness Gut bacteria Transfers through ingestion on unclean water and contact with infected feces
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Protist Biology Protozoan flagellate Giardia lamblia Cysts survive well in water 2 trophozoites released in small intestine Multiply within host Return to cyst state Protective outer shell Flagella for movement in trophozoite stage
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Who is at Risk? Anyone More common in children than adults People in contact with children Travelers where the disease is common Those in contact with infected people Swallowing contaminated water Using or consuming untreated water
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Common Symptoms Diarrhea Gas Stomach or abdominal cramps Upset stomach Nausea Vomiting Dehydration
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Treatment Nitroimidazole drugs 5 to 7 days of treatment If resistant to 5-7 day treatment: longer doses are given Quinacrine is also given
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Disease Prevention Good hygiene, Avoid potentially contaminated water and food Practice protected sex Clean up after pets Clean surfaces Non chlorine based cleansers
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Statistics Around 200 million people are infected each year
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Works Cited Centers for Disease Controls and Preventions. (2015, July 21). Parasites - Giardia. Retreved from https://www.cdc.gov/parasites/giardia/general-info.html Gardner, T. B., & Hill, D. R. (2001). Treatment of giardiasis. Clinical microbiology reviews, 14(1), 114-128. Khanna, R., Vinayak, V. K., Mehta, S., & Nain, C. K. (1988). Giardia lamblia infection in immunosuppressed animals causes severe alterations to brush border membrane enzymes. Digestive diseases and sciences, 33(9), 1147-1152. Nazer, H. (2018, October 1). Giardia. Retreved from https://emedicine.medscape.com/article/176718-overview#a5 Thompson, R. C. A., Reynoldson, J. A., & Mendis, A. H. W. (1993). Giardia and giardiasis. In Advances in parasitology(Vol. 32, pp. 71-160). Academic Press. United States Environmental Protection Agency (2000). Giardia: Drinking Water Fact Sheet. Retrieved September, 2000 from https://www.epa.gov/sites/production/files/2015-10/documents/giardia-factsheet.pdf