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Childhood Cancer: Incidence Survival and Mortality PowerPoint Presentation

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Description : Check out this medical presentation on Childhood Cancer, which is titled "Childhood Cancer: Incidence, Survival and Mortality", to know about the incidence and survival of various types of cancer in kids and how these parameters are affected by age, race / ethnicity, and gender.

Tags : Childhood Cancer, Incidence, Survival, Mortality, types of cancer, kids

Published on : May 13, 2021 | Views : 1365 | Downloads : 4

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Slide 1-

Childhood Cancer: Incidence, Survival and Mortality Pediatric Resident Education Series
Slide 2-

Childhood Cancer Purpose is to describe the incidence and survival of various types of cancer in kids and how these parameters are affected by: Age Race / Ethnicity Gender
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Childhood Cancer General Statistics: Approximately 12,400 new diagnoses/year < 20 yo 0-14 = 8,700 15-19 = 3,700 Thus, incidence is 150 per million children < 20 yo newly diagnosed with cancer each year, or 1/ 7,000 The probability of a newborn developing cancer by age 20 is between 0.3 – 0.32%, or ~ 1/300 1,500-1,600 deaths/year in children < 15 years of age
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Overall Trends Incidence relatively stable Mortality declining
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Age Specific Incidence Rates for Childhood Cancers
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Age Specific Incidence Rates for Childhood Cancers Incidence rate similar for youngest (< 5 yr) and oldest (15-19 yr) age groups But… histologies (or types of cancer) are different in these groups
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Incidence distribution by histology children < 5 yrs vs. > 15 yrs
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Age Specific Incidence Rates for Childhood Cancers
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Age Specific Incidence Rates for Childhood Cancers Most common cancer < 15 yrs – leukemia > 15 yrs – lymphoma Second most common < 10 yrs – CNS tumors 10-14 yrs – lymphoma > 15 yrs – leukemia
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Distribution of Specific Cancer Diagnoses for Children and Adolescents
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Incidence of Cancers is Influenced by Race/Ethnicity
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Incidence of Cancers is Influenced by Race/Ethnicity – US data 1990-95 In adults, incidence of cancer more common in blacks than whites For children, cancer was less common in blacks than whites Incidence for Hispanic & Asian/Pacific islanders intermediate between blacks and whites American Indians had the lowest incidence of any group
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Incidence of Cancers is Influenced by Race/Ethnicity
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Incidence of cancer influenced by gender Generally higher in males than females Some histologies show gender predisposition Age may also influence sex distribution e.g. Hodgkins Age < 15 yrs male > female Age > 15 yrs female > male
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Trend in Survival Rates for Childhood Cancer – overall & specific
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Trend in Survival Rates for Specific Childhood Cancers
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Trend in Survival Rates for Specific Childhood Cancers – influence of age
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Leading Causes of Death in Children < 14 y/o in the USA 1997
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Leading Causes of Death in Adolescents in the USA 1997
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The converse of survival... Overall Mortality rate decreasing
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Distribution by Cause of Cancer Death Overall distribution of incidence by cancer type
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Mortality Rates for Childhood Cancers
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Age-specific cancer mortality… Related to incidence and type of cancer in the age groups
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Age-specific cancer mortality…
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Age-specific cancer mortality…
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Summary Cancers of children represent a diverse group of diagnoses with a distinctive age-incidence pattern The incidence of cancer among children has remained essentially stable over several decades The mortality rates for all cancer types have decreased dramatically over the last several decades
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Credits Information and tables, for the most part, taken from the SEER monograph on Childhood Cancer Cancer Incidence and Survival Among Children and Adolescents: United States SEER Program 1975-1995 http://seer.cancer.gov/publications/childhood/ Other tables taken from Gurney JG & Bondy ML, “Epidemiology of Childhood Cancer”, in Principles and Practice of Pediatric Oncology, 5th ed, Pizzo PA and Poplack DA, eds, LWW, 2005. http://www.lww.com/static/docs/product/samplechapters/0-7817-5492-5_Chapter%201.pdf Michael Kelly MD PhD Anne Warwick MD MPH